Tumor-infiltrating CD45RO+ memory cells correlate with favorable prognosis in patients with lung adenocarcinoma
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چکیده
منابع مشابه
High expression of CD8 predicts favorable prognosis in patients with lung adenocarcinoma
Lung carcinoma is the most common cause of malignant death worldwide. CD8 T cells, as critical elements in antitumor immunity, could function as good prognostic indicators in various kinds of cancers such as renal cell carcinoma and colorectal cancer, but its prognostic role in lung adenocarcinoma is still unclear. The objective of this study was to explore the prognostic role of CD8 expression...
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Conventional chemotherapy for lung cancer exerts anti-tumor effects through cytotoxicity, and through immunologic regulation by reducing specific T cell subsets and inducing the expression of programmed death ligand 1 (PD-L1) on tumor cells. Even though pemetrexed has shown huge potential in combination with other targeted or immune therapies, there is still little information about the values ...
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MAP3K3 is involved in both the immune response and in tumor progression. Its potential biological role in vitro in lung cancer cell lines and the association of mRNA/protein expression patterns with clinical outcome of primary lung tumors were investigated in this study. Silencing MAP3K3 using siRNA in lung cancer cell lines resulted in decreased cell proliferation, migration and invasion. Thes...
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چکیده ندارد.
Tumor-infiltrating macrophages correlate with adverse prognosis and Epstein-Barr virus status in classical Hodgkin lymphoma
Background. Classical Hodgkin lymphoma is characterized by a minority of neoplastic cells surrounded by a heterogeneous background population of non-neoplastic cells including lymphoma associated macrophages. High levels of expression of both the monocytes/macrophage lineage associated antigens CD68 and CD163 have been suggested to have protumoral effects. The aim of our study was to correlate ...
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ژورنال
عنوان ژورنال: Journal of Thoracic Disease
سال: 2018
ISSN: 2072-1439,2077-6624
DOI: 10.21037/jtd.2018.03.148